EFEKTIVITAS ANTIBAKTERI NANO KITOSAN TERHADAP PERTUMBUHAN Staphylococcus aureus (in vitro)
Abstract: Mouth is considered
as a not homogeneous environment. These following aspects may caused a
significant contribution towards the cause of infection namely; the mucosal
surfaces in the mouth and teeth are not the same, has warm temperatures,
moisture and nutrient-rich environment which increasing the growth of
microorganisms. Staphylococcus aureus can trigger the occurrence of infectious
diseases, which is acute apical abscess. Nano chitosan is a physical
modification of chitosan which posses antibacterial capability. The purpose of
this study to test the effectiveness of antibacterial nano chitosan in
different degree of deacetylation and concentrations against Staphylococcus
aureus. This experimental study was conducted with disc’s method and using some
concentration of 90%, 45%, 22,5%, 11,25%, 5,625%, 2,812%, 1,406%, 0,703%,
0,351%, 0,175% and 2 control groups, namely positive and negative controls. The
statistical analysis using Chi - Square manually. The test results of
antibacterial activity against S. aureus is the Minimum Inhibitory
concentration (MIC) of nano chitosan DD 89% and 93% at a concentration of
22.55%. Minimum Bactericidal Concentration (MBC) nano chitosan DD 89% is at a
concentration of 45% , while the nano chitosan DD 93% at a concentration of
22.5% . The results of statistical tests showed there are differences of MIC
and MBC at different concentrations but there is no difference on different the
degree of deacetylation test.
Penulis: Ade Komariah
Kode Jurnal: jpbiologidd140171
