DAYA ANTIFUNGAL EKSTRAK ETANOL DAUN (Piper aduncum) DAN (Piperomia pellucida) TERHADAP PERTUMBUHAN (C. albicans) SECARA INVITRO
Abstract: Sesuruhan plants
(Piper aduncum) and messengers (Piperomia pellucida) is a species of Piperaceae
familia members. Both of these plant species containing antifungal compounds
include: tannins, flavonoids, and saponins. Candida albicans is a yeast causing
vaginal discharge disease. Antifungal potential of ethanol extract of the
plant, particularly against C. albicans in vitro testing needs. The purpose of
this study is to: 1) examine the effect of ethanol extract of leaves sesuruhan
in some sort of concentration on the inhibition of growth of C. albicans in
vitro; 2) examine the effect of ethanol extract of leaves of messengers in some
sort of concentration on the inhibition of growth of C. albicans in vitro; 3)
determine the most effective concentration of the ethanol extract of leaves and
leaf sesuruhan messengers in some kind of concentration to inhibit the growth
of C. albicans in vitro. Extracts of both species was obtained by maceration
method with 95% ethanol, followed by sterile filtration and evaporation of the
filtrate thus obtained. Filtrate was diluted in 10 concentration levels,
namely: 0%, 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, and 90%. Testing the two
kinds of power antifungal leaf species was conducted using agar diffusion
technique of pitting on Sabouraud Dextrose Agar medium that has been inoculated
with C. albicans. Measurement of C. albicans growth inhibitory zone performed
after an incubation period of 1x24 hours. The results of this study are: 1)
There is no effect of ethanol extract of leaves sesuruhan in some sort of
concentration on the inhibition of growth of C. albicans in vitro. The higher
the concentration of the ethanol extract of the leaves sesuruhan increasing
inhibition of growth of C. albicans; 2) There is no effect of ethanol extract
of leaves of messengers in some sort of concentration on the inhibition of
growth of C. albicans in vitro. The higher the concentration of the ethanol
extract of the leaves of messengers increasing inhibition of growth of C.
albicans; 3) Ethanol extract of leaves and leaf sesuruhan errand at a
concentration of 80% was the most effective concentration to inhibit the growth
of C. albicans in vitro.
Penulis: Utami Sri Hastuti
Kode Jurnal: jpbiologidd140122
