Efektivitas Kanamycin terhadap Furunculosis pada Karper, Cyprinus carpio
Abstract: The aim of
experiment was to know the appropriate and effective dosis of kanamycin
antibiotic in order to recover and clean the Aeromonas salmonicida which caused
furunculosis in carp, Cyprinus carpio. The experiment consisted of the
preliminary test [revirulence of A. salmonicida, sensitivity, minimum
inhibitory concentration (MIC), minimum bactericidal concentration test (MBC),
lethal concentration-50 (LC50) of A. salmonicida to carp] and the effectiveness
antibiotic kanamycin test. The water quality was analyzed at the beginning and
the end of the experiment, histopathology was analyzed at the end of the
experiment. The data were analyzed using analysis of variance (ANOVA) continued
by least significant different and regression tests.
Based on the result of in vitro test, it was obtained that the value of
MIC was 4 ppm and the value of MBC was 8 ppm, while the result of lethal
concentration-50 (LC50) A. salmonicida to carp was 1.07 x 105 cell/ml. Survival rate of carp at the end of
experiment were 20% (treatment 0 ppm); 73,3% (treatment 16 ppm); 86.7%
(treatment 32 ppm); 93.3% (treatment 48 ppm); 96.7% (treatment 64 ppm); and
100% (treatment 80 ppm). The survival rates were very significance difference
(P <0,01) among treatments and the treatments of kanamycin were very
significant difference (P <0.01) from positif control. The regression showed
that there was correlation between the concentration of kanamycin and survival
rates of carp by coefficient of correlation (R2) at 0.9382.
Keywords: Aeromonas
salmonicida, carp, effectiveness, kanamycin
Penulis: Sri Retnoningsih,
Kamiso H. Nitimulyo, Kardiman Lanadimulya, Suprayogi, Supardi, Djoko
Darmantani, I P. Panca, Hasnah, Soefaad, Milis
Kode Jurnal: jpperikanandd090013
