PENGARUH PEMBERIAN TIMBAL (Pb) DOSIS KRONIS SECARA ORAL TERHADAP PENINGKATAN PENANDA KERUSAKAN ORGAN PADA MENCIT
Abstract: Several kind of
heavy metals that
present in the
environment are considered
as toxic substance to human and
animal. Lead (Pb) is one of heavy metals that increase in use for the last
decade. Lead toxicity
to human had
wide influence in
medical aspect, from
nerve problem, bone metabolics disturbance until liver and renal
failure. This experiment tried to found out the effect of cronic oral lead consupmtion
to lead plasma rate in mice. Design of this
experiment is true
research experiment to
test wheater there
is an effect
of oral lead consumption to
acumulation of lead
in blood plasma
of mice. The
dose devided to two
kinds, medium dose (50 ppm) and high dose (100 ppm). The results show increase of
lead accumulation in blood plasma of the mice compared to control group.
Key word: Lead, accumulation, toxicity, blood pasma, mice
Penulis: Abdul Malik Setiawan
Kode Jurnal: jpbiologidd120038
