PENGARUH EKSTRAK SEGAR DAUN ROSELA (Hibiscus sabdariffa L.) TERHADAP JUMLAH ERITROSIT DAN KADAR HEMOGLOBIN MENCIT JANTAN (Mus musculus L.) ANEMIA STRAIN DDW MELALUI INDUKSI NATRIUM NITRIT (NaNO2)
Abstrack: The
purpose of this research is to investigate the effect of fresh leave extract of
rosela (Hibiscus sabdariffa L.) on erythrocyte
and haemoglobin concentration
in anemia male
mice (Mus musculus
L.) DDW strain induced by sodium nitrite. Completely
randomized design (CRD) was used in this experiment, consisting of 5 groups.
The first two groups is control induced by NaNO2 for 18 days and the second
group is induced by NaNO2 for 18 days and then distilled water for 14 days, and
three groups of teratment. The treatment group, divided into three classes of
concentration such as; 14 mg/ml (P1), 28 mg/ml (P2) and 42 mg/ml (P3). The treatment
group induced by NaNO2 first for 18 days and then healing process by extract of
rosela leaves for 14 days. Each class consisted of six experiments animals. The
extract was given orally 0.3
ml/day. The results indicate
that leave extract
affect on increasing
of erythrocytes and
hemoglobin concentration that have a significantly different
(p<0.05) between control and
treatments.
Keyword:
anemic, erythrocytes, haemoglobin, rosela leaves
Penulis: Asmitra
Sembiring, Masitta Tanjung, dan Emita Sabri
Kode
Jurnal: jpbiologidd130026
