UJI PENURUNAN KADAR GLUKOSA DARAH OLEH EKSTRAK ETANOL 70% DAUN BUNCIS (Phaseolus vulgaris L) PADA KELINCI JANTAN YANG DIBEBANI GLUKOSA
Abstract: This research aim to
know the descent of blood glucose rate by extract etanol 70% of bean leaf at
male rabbit which induced glucose. Research using the method test glucose
tolerance of oral was including category research of sham eksperimental with
complete random attempt device of unidirectional pattern. This research use 20
male rabbits which divided in 5 treatment group. Group I given by CMC Na 1% as
negative control, group II given by acarbose suspensi 2,33 mg/kgBB as positive
control, group III, IV and V given by extract etanol 70% bean leaf with each
dose 200, 300 and 450 mg/kgBB. Treatment given at once after test animal
induced glucose 50% ( 5 ml/1,5 kgBB). Glucose blood rate to define every 30
minute, 0 minute until 300 minutes by using method of enzimatik GOD PAP
(Glucose Oxidase Phenol Aminoantipyrina Peroxidase), what was later then
analysed with one track Anava and continued by test of LSD (Least Significant
Diffeerence) with trust level 95%. Extract etanol 70% bean leaf with dose 200,
300 and 450 mg/kgBB have effect descent of blood glucose rate to negative
control of CMC Na 1% (p = 0,000) with each percentage descent of blood glucose
rate (% PKGD) 80,88 ± 0,93 ; 82,73 ± 0,67 and 85,32 ± 0,21.
Penulis: Desy Kurniawati, EM
Sutrisna, Arifah Sri Wahyuni
Kode Jurnal: jpkedokterandd120216
