UJI EFEKTIVITAS EKSTRAK ETANOL BERAS MERAH TERHADAP PENURUNAN KADAR GLUKOSA DARAH PADA TIKUS WISTAR (Rattus norvegicus) YANG DIBERI BEBAN GLUKOSA
Abstract: Diabetes mellitus (
DM ) is a disease in which the body can not produce insulin ( a hormone
regulating blood glucose ) . Therefore, it would lead to increased blood sugar
when examined . Food plays a role in the increase in blood glucose levels .
Despite the fibrous foods that contain carbohydrates , but still takes time to
go through the digestive system , so it has a low glycemic index . Red rice
good for diabetics because it has a lower glycemic index than white rice .
Utilization of animal experiments carried out to rule the diagnosis in the
event of food poisoning , it can be selected Wistar rats as test animals . This
study aims to determine the effectiveness of red yeast rice in lowering blood
glucose levels in Wistar rats given glucose load . There is a significant
result in the group treated with ethanol extract of red rice 500mg/kg and
1000mg/kg bb bb the results are within the normal range . Although the
treatment with 100mg/kg body weight of rats , the results are not up to the
range of blood glucose levels in the range of normal mice . This is caused by
the concentration of ethanol extract of red rice is low . This study also shows
that there are differences in blood glucose levels significantly in each
treatment group and at the time of treatment with the vulnerable period of the
30th minute to minute 120 . Anti- diabetic effects produced by drug
glibenclamide can be used as positive controls with normal results . Conclusion
The ethanol extract of red yeast rice is effective against falling glucose levels
Wistar rats were given based on the concentration of glucose load and scan
times .
Penulis: Dyan R. Sukandar,
Immanuel G. Poernomo
Kode Jurnal: jpkesmasdd130517
