UJI EFEKTIVITAS EKSTRAK ETANOL BERAS MERAH TERHADAP PENURUNAN KADAR GLUKOSA DARAH PADA TIKUS WISTAR (Rattus norvegicus) YANG DIBERI BEBAN GLUKOSA
Abstract: Diabetes mellitus ( DM ) is a disease in which the body can not produce insulin ( a hormone regulating blood glucose ) . Therefore, it would lead to increased blood sugar when examined . Food plays a role in the increase in blood glucose levels . Despite the fibrous foods that contain carbohydrates , but still takes time to go through the digestive system , so it has a low glycemic index . Red rice good for diabetics because it has a lower glycemic index than white rice . Utilization of animal experiments carried out to rule the diagnosis in the event of food poisoning , it can be selected Wistar rats as test animals . This study aims to determine the effectiveness of red yeast rice in lowering blood glucose levels in Wistar rats given glucose load . There is a significant result in the group treated with ethanol extract of red rice 500mg/kg and 1000mg/kg bb bb the results are within the normal range . Although the treatment with 100mg/kg body weight of rats , the results are not up to the range of blood glucose levels in the range of normal mice . This is caused by the concentration of ethanol extract of red rice is low . This study also shows that there are differences in blood glucose levels significantly in each treatment group and at the time of treatment with the vulnerable period of the 30th minute to minute 120 . Anti- diabetic effects produced by drug glibenclamide can be used as positive controls with normal results . Conclusion The ethanol extract of red yeast rice is effective against falling glucose levels Wistar rats were given based on the concentration of glucose load and scan times .
Penulis: Dyan R. Sukandar, Immanuel G. Poernomo
Kode Jurnal: jpkesmasdd130517