The Role of a Novel Digital Microcapillary Instrument in Detecting Blood and Plasma Hyperviscosity

ABSTRACT: to test the precision and accuracy of a Digital Microcapillary instrument in measuring blood and plasma viscosity. Methods: about 40 blood samples were drawn for precision test. The samples were obtained from patients admitted for Medical Check-Up at CiptoMangunkusumo Hospital (RSCM) in December 2011. Accuracy test was evaluated using cross-sectional design and involving 135 patients with acute ischemic stroke. The patients underwent either inpatients or outpatients care at Department of Clinical Pathology, Department of Neurology,and Emergency Unit of RSCM, Fatmawati Hospital Jakarta, Prikasih Hospital Jakarta, and Bhakti Yuda Hospital Depok. The precision test was evaluated by calculating the coeffcient of variation (CV), interrater variability of Cronbach Alpha, and reliability coeffcient of Bland Altman. The accuracy of the test was evaluated with a diagnostic test. The gold standard used for these tests was Brookfeld LV-DV III viscometer. Results: the results of precision test were: CV = 0.04; interrater variability of blood and plasma viscosity = 0.94 and 0.82, respectively; the Bland Altman mean difference = –0.19. The results of accuracy test were: sensitivity of blood and plasma viscosity measurement were 88.9% and 100%, respectively; specifcity of blood and plasma viscosity measurement were 88.9% and 84%, respectively. Conclusion: the digital microcapillary has high sensitivity and specifcity; therefore the instrument can be considered to be used as screening test tool to measure blood and plasma viscosity.
Key words: digital microcapillary, blood viscosity, plasma viscosity, acute ischemic stroke
Author: Al Rasyid, Jusuf Misbach, Jan S. Purba, Ina S. Timan, Lugyanti Sukrisman, Muchtaruddin Mansyur, Efa Yudiarsah, Suroto
Journal Code: jpkedokterangg140287

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