The Role of a Novel Digital Microcapillary Instrument in Detecting Blood and Plasma Hyperviscosity
ABSTRACT: to test the
precision and accuracy of a Digital Microcapillary instrument in measuring
blood and plasma viscosity. Methods: about 40 blood samples were drawn for
precision test. The samples were obtained from patients admitted for Medical
Check-Up at CiptoMangunkusumo Hospital (RSCM) in December 2011. Accuracy test
was evaluated using cross-sectional design and involving 135 patients with
acute ischemic stroke. The patients underwent either inpatients or outpatients
care at Department of Clinical Pathology, Department of Neurology,and Emergency
Unit of RSCM, Fatmawati Hospital Jakarta, Prikasih Hospital Jakarta, and Bhakti
Yuda Hospital Depok. The precision test was evaluated by calculating the
coeffcient of variation (CV), interrater variability of Cronbach Alpha, and reliability
coeffcient of Bland Altman. The accuracy of the test was evaluated with a
diagnostic test. The gold standard used for these tests was Brookfeld LV-DV III
viscometer. Results: the results of precision test were: CV = 0.04; interrater
variability of blood and plasma viscosity = 0.94 and 0.82, respectively; the
Bland Altman mean difference = –0.19. The results of accuracy test were: sensitivity
of blood and plasma viscosity measurement were 88.9% and 100%, respectively;
specifcity of blood and plasma viscosity measurement were 88.9% and 84%,
respectively. Conclusion: the digital microcapillary has high sensitivity and
specifcity; therefore the instrument can be considered to be used as screening
test tool to measure blood and plasma viscosity.
Author: Al Rasyid, Jusuf
Misbach, Jan S. Purba, Ina S. Timan, Lugyanti Sukrisman, Muchtaruddin Mansyur,
Efa Yudiarsah, Suroto
Journal Code: jpkedokterangg140287
