The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
ABSTRACT: to obtain
information on the proportion of orthostatic hypotension in elderly patients
with diabetes and its relationship with HbA1c levels. Methods: this is a
cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60
years old who sought treatment at outpatient clinic of Geriatry and Diabetes
Division at Cipto Mangunkusumo Hospital between January and March 2016.
Orthostatic hypotension was defned as a decrease in systolic blood pressure ≥20
mmHg and/or diastolic pressure ≥10 mmHg within 3 minutes after changing
position from lying to standing. HbA1c levels was measured using Nycocard from
Axis Shield. Chi square test was used for bivariate analysis and logistic
regression was used for multivariate analysis against confounding variables. Results:
the proportion of orthostatic hypotension in elderly subjects with DM was
27.4%. Median of HbA1c levels was higher in subjects with than without
orthostatic hypotension (7.6% vs. 7.1%; p<0.05). There was an association
between HbA1c levels of ≥7.35% and the incidence of orthostatic hypotension (OR
1.987, 95% CI 1.2-3.2). The duration of having DM was a confounding variable.
Conclusion: orthostatic hypotension is more common in elderly subjects with DM.
There is an association between the incidence of orthostatic hypotension and
increased HbA1c levels in elderly patients with diabetes mellitus.
Author: Catarina Budyono, Siti
Setiati, Dyah Purnamasari, Cleopas M. Rumende
Journal Code: jpkedokterangg160001