The effect of moderate-intensity acute aerobic exercise duration on the percentage of circulating CD31+ cells in lymphocyte population
Abstract: The increasing
number of circulating CD31+ endothelial progenitor cells is one of the
important factors for maintaining vascular homeostasis. Exercise will
effectively increase the number of circulating CD31+ endothelial progenitor
cells. This study aims to determine the effect of moderate-intensity acute
aerobic exercise duration on the percentage of circulating CD31+ cells in
untrained healthy young adult subjects.
Methods: This study was an experimental study. Untrained healthy
volunteers (n=20) performed ergocycle at moderate-intensity (64–74% maximum
heart rate) for 10 minutes or 30 minutes. Immediately before and 10 minutes
after exercise, venous blood samples were drawn. The percentage of CD31+ cells
in peripheral blood was analyzed using flow cytometry. Data was statistically
analyzed using student t-test.
Results: There were no significant differences in the mean percentage of
circulating CD31+ cells before and after exercise for 10 minutes and 30 minutes
(p>0.05). However, there was a different trend in the percentage of
circulating CD31+ cells after exercise for 10 minutes and 30 minutes. In the 10
minutes duration, 50% of subjects showed increase. Whereas in the 30 minutes
duration, 80% of subjects showed increase.
Conclusion: The percentage of circulating CD31+ cells before and after
exercise for 10 minutes was not different compared to 30 minutes. However, data
analysis shows that majority of subjects (80%) had increased in the percentage
of circulating CD31+ cells after 30 minutes exercise.
Keywords: CD31+ peripheral
blood mononuclear cells; circulating endothelial progenitor cells; endothelial
regeneration; exercise
Author: Mariani Santosa,
Ermita I.I. Ilyas, Radiana D. Antarianto
Journal Code: jpkedokterangg160139
