Profle and Factors Associated with Mortality in Mediastinal Mass During Hospitalization at Cipto Mangunkusumo Hospital, Jakarta
ABSTRACT: Aim: to obtain
characteristics, variations of the type of mass, diagnostic modalities, and
mortality factors during hospitalization in patients with mediastinal mass at
our institute during a 10-year period. Methods: a case-control study was
conducted, by browsing through the medical records of 113 mediastinal mass
patients who were treated at Cipto Mangunkusumo Hospital, Jakarta, during a
10-year period (January 2000-December 2009). Factors associated with mortality,
i.e; sepsis, septic shock, pneumonia, lung tuberculosis, superior vena cava
syndrome, massive pleural effusion, pericard effusion, and respiratory failure
were analyzed by logistic regresion multivariate analysis. Results: two hundred
and one mediastinal mass patients were diagnosed and treated at our institute, 113
medical records were available to be included in this study. There were 69
males and 44 females with the anteriosuperior
compartement. Chest X-ray imaging were able to detect 61 cases of mediastinal
mass, while 42 patients underwent thoracotomy (open biopsy) to acquire
histopathology diagnosis. The proportion of mortality during hospitalization
reached 39.8%. Logistic regression multivariate analysis found sepsis
(p=0.000), superior vena cava syndrome (p = 0.000), and massive pleural
effusion (p=0.047), were signifcant factors associated with mortality during
hospitalization. Conclusion: the clinical and radiologic features of
mediastinal mass patients in our institute showed that mediastinal mass may
resemble the symptoms of other diseases. Types and diagnostic modalities
performed in our study differs from other studies previously reported in other
countries with a high proportion of mortality during hospitalization.
Author: Gurmeet Singh, Zulkifli
Amin, Wuryantoro, Valy Wulani, Hamzah Shatri
Journal Code: jpkedokterangg130247
