PENGARUH PEMBERIAN PROBIOTIK LACTOBACILLUS HELVETICUS ROSELL-52 DAN LACTOBACILLUS RHAMNOSUS ROSELL-11 TERHADAP KADAR LIMFOSIT LANJUT USIA
ABSTRACT: Infectious disease
remains a health problem for the elderly. The elderly are susceptible to
infection,because the body's ability to fight infection decreases immunity. The
immune status can be improved through the effortsof immunization, and
nutrition. However the elderly are not sufficient to meet the nutritional needs
of food, so probioticcould support nutritional adequacy.Objective: Analyze the
effect of probiotic Lactobacillus helveticus Rosell-52 and Lactobacillus
rhamnosus Rosell-11 onlevels of lymphocytes in the elderly in Tresna Elderly Social
Institution Puspakarma Mataram, West Nusa Tenggara.Methods: This was
quasi-experimental study, randomized pre-post control group design. The
population is elderly aged60-75 years, involving 45 subjects were divided
randomly into two groups, namely the treatment groups givenprobiotics and the
control group was given a placebo. Probiotics were given for 4 weeks, with the
provision of onecapsule a day. Immunity status in this study was lymphocytes.
Data examined included the intake of nutrients (protein,vitamin A, vitamin C,
vitamin E, Fe, Zn), health status, quality of sleep, and levels of lymphocytes
in the elderly. Datawere analyzed using bivariate with different test
Independent sample t-test, Mann-Whitney U test, Spearman, Pearson,and Paired
t-test.Results: Increasing number of lymphocytes were significantly in the
treatment group (χ ± SD: 1.84 ± 1.85) and in thecontrol group (0.95 ± 5.0).
There is no relationship between intake (protein, vitamin A, vitamin C, vitamin
E, Fe, Zink),physical health status, and quality of sleep with levels of
lymphocytes.Conclusion: Probiotics in 4 weeks is proven to increase the number
of lymphocytes in the elderly.
Penulis: Retno Wahyuningsih,
Darmono SS, Ani Margawati
Kode Jurnal: jpkesmasdd140411