PEMBERIAN ASAM LEMAK TIDAK JENUH OMEGA 3 TERHADAP PENURUNAN KADAR ASAM URAT PADA PENDERITA ASAM URAT (GOUT) PASIEN RAWAT JALAN RSUP Prof. dr. R.D. KANDOU MANADO
Abstract: Uric acid (gout) is characterized by uric acid levels were persistently elevated in the blood (hyperuricemia) having a concentration greater than 7 mg/dl in men and 6 mg/dl in women. Provision of unsaturated fatty acids Omega 3 can reduce inflammation and pain in the new joint study on rheumatoid arthritis and osteoarthritis patients.The purpose of this study was to determine the effect of food supplementation of unsaturated fatty acids Omega 3 to decrease uric acid levels in patients with uric acid (gout) in the outpatient department of Prof.dr. R.D. Kandou Manado. This research is a Clinical Trial with Non- randomized study designs quasi experimental Concurrent Control Trial (Non- Equivalent Control Group Design With Pre Test and Post Test). The treatment group was given food supplements unsaturated fatty acids Omega 3 at a dose of 600 mg / day , and the control group was not given Omega 3, but given Vitamin E 100 g per day as a placebo. Samples were people with gout/hyperuricemia (gout). The data collected by interview (characteristics of the sample) and uric acid levels (lab results) after 8 weeks of consuming omega 3. Data analysis using the t test and paired . The result there is a decrease in blood levels of uric acid in the treatment group (from 8.30 mg/dl to 7,28 mg/dl) when compared with the levels of uric acid in the blood in the control group ( from 8.22 mg / dl to 8 , 64 mg/dl) . Changes in uric acid levels in the treatment group was statistically (Paired) had a difference (difference decreases) were highly significant with a value of t = 5.832 (p = 0.000). Results of statistical tests (t test) of the differences in levels of uric acid in the two groups (treatment and control) showed a significant difference with p = 0.004 (p < 0,05). Conclusions are the effect of Omega 3 fatty acids to decrease uric acid levels.
Penulis: Rudolf Boyke Purba, Olga Paruntu, Olfie Sahelangi
Kode Jurnal: jpkesmasdd130510