Hipoalbuminemia prabedah sebagai faktor prognostik enterokolitis pascabedah penderita megakolon kongenital (Hirschsprung’s disease)
Abstract: Hirschsprung’s
disease or congenital megacolon is the congenital absence of ganglion cells in
the colon. The rectum is always involved and in 90% of patients the abnormality
is confined to the rectum and sigmoid. Absence of ganglion cells prevents
peristalsis, resulting in functional obstruction. The success of Hirschsprung’s
treatment depends on many factors such as age at the time of operation, body
weight, hemoglobin levels, albumin levels, length of operation, length of stay
and other prognostic factors. Post operative enterocolitis and other
complications still represent as the problem wich often are faced by pediatric
surgeons.
Objective: The aim of this study was to evaluate the effect of albumin
levels on postoperative enterocolitis in children presenting with congenital
megacolon.
Method: We conducted an ambidirectional cohort study involving children
presenting with Hirschsprung’s disease in Dr. Sardjito, Panti Rapih and Permata
Husada hospitals in Yogyakarta city from January 2005 to December 2010. All
children had been operated using ERPT and PSNRHD methods. The subjects were
classified into normoalbuminemia (>3.5 g/dl) and hypoalbuminemia (≤3.5
g/dl). The effect of albumin levels on postoperative enterocolitis were
indicated by relative risk and 95% confidence interval.
Results: Out of 104 children with Hirschsprung’s disease, 53 (51%) were
hypoalbuminemic and 51 (49%) were normoalbuminemia. Postoperative enterocolitis
was found in 18 (17.3%) children, 11/18 (61.1%) of them were hypoalbuminemia,
whereas 7/18 (38.9%) were normoalbuminemia. Albumin levels were not significant
prognostic factor for postoperative enterocolitis in children with congenital
megacolon (RR=1.51; 95% CI:0.64-3.60; p=0.34).
Conclusion: The albumin levels are not prognostic factor for
postoperative enterocolitis in children with congenital megacolon.
Penulis: Rochadi
Kode Jurnal: jpkesmasdd130599
