Formulation and Physical Test of Ethanolic Extract Sambiloto Leaves (Andrographis paniculata) Ointment
ABSTRACT: Andrographis
paniculata had known contained active substance such as andrographolida, atsiri
oil, flavonoid, tannin, alkaloid, and saponin which functions as antibacterial,
antitoxic, analgesic, and anti-pyretic. Based on its antibacterial properties,
an ointment form of Andrographis paniculata leaf is then formulated, for
practical usage. Ointment formula is semi solid for topical use in the skin or
mucosal membranes. Objectives: to know the result of ointment physical test of
etanolic extract Andrographis paniculata leaf.
Methods: physical tests contain organoleptic test, pH, homogenity,
adhesion test and dispersive test.
Results: Ointment shaped semi solid, blacky green and special smell of
Andrographis paniculata, pH 6, homogenity test obtained homogenous results, adhesion
test was 82 second and dispersive test was 5.6 cm.
Conclusion: the result of physical tests of etanolic Andrographis
paniculata leaf extract ointment appropriate with quality standard.
Author: Indri Kusuma Dewi,
Titik Lestari, Siti Nur Rofi’ah
Journal Code: jpkedokterangg150295
