Factors Associated with In-stent Restenosis in Patients Following Percutaneous Coronary Intervention
ABSTRACT: to determine factors
associated with In-Stent Restenosis (ISR) in patients following Percutaneous Coronary
Intervention (PCI). Methods: a retrospective cross-sectional study was
conducted using secondary information from medical records of post-PCI patients
who underwent follow-up of angiography PCI between January 2009 and March 2014
at The Integrated Cardiovascular Service Unit, Cipto Mangunkusumo Hospital, Jakarta.
Angiographic ISR was defned when the diameter of stenosis ≥50% at follow-up
angiography including the diameter inside the stent and diameter with fve-mm
protrusion out of the proximal and distal ends of the stent. Results: there
were 289 subjects including 133 subjects with and 156 subjects without ISR. The
incidence of ISR in patients using of bare-metal stent (BMS) and drug-eluting
stent (DES) were 61.3% and 40.7%, respectively. Factors associated with ISR are
stent-type (OR=4.83, 95% CI 2.51-9.30), stent length (OR=3.71, 95% CI 1.99- 6.90),
bifurcation lesions (OR=2.43, 95% CI 1.16-5.10), smoking (OR=2.30, 95% CI
1.33-3.99), vascular diameter (OR=2.18, 95% CI 1.2-3.73), hypertension
(OR=2.16, 95% CI 1.16-4.04) and diabetes mellitus (OR=2.14, 95% CI 1.23-3.70).
Conclusion: stent type, stent length, bifurcation lesions, smoking, vascular
diameter, hypertension and DM are factors associated with ISR in patients
following PCI.
Author: Dedi Wihanda, Idrus
Alwi, Muhammad Yamin, Hamzah Shatri, E. Mudjaddid
Journal Code: jpkedokterangg150244
