Effect of Cognitive Behavior Therapy (CBT) Intervention on Serum Cortisol Level and Pain Score of Patients with AdvancedStage Cervical Cancer
ABSTRACT: Cervical cancer is
the most frequent cause of death related gynecology malignancy in Indonesia.
Recent management of advanced-stage cervical cancer has still not been able to
improve the prognosis. Chemotherapy and radiation intervention, as well as
therapy may resulting pain and cause psychological stress for some patient,
furthermore it couldeffect on the quality of life. Cortisol is a hormone of
adrenal cortex, it secretes due to increased production of ACTH by anterior
pituitary which is associated with stressful condition. Cognitive behavioral
therapy (CBT) is expected to help subdue stress and reduce pain in patients
with advanced cancer, which will bring positive impact on the patients by
improving their quality of life. In this study, we wished to analyze the effect
of Cognitive Behavior Therapy (CBT) intervention on serum cortisol levels and
pain score of patients with advanced-stage cervical cancer. This experimental
study was a double blind non-randomized clinical trial post-test group design.
It was using two groups in this study, each group consisting of 15 subjects,
the treatment group were given CBT and standard therapy, while the control
group were only given a standard therapy. The study was conducted in the
gynecology oncology ward and the gynecology oncology clinic of Dr. Moewardi
Hospital Surakarta and Prodia Laboratory, from January - March 2015. Our study
showed that cortisol level of the treatment group was 1.03 ± 0.71 mg / dL, and the
control group was 11.41 ± 7.34 mg / dL (p = 0.00). Pain score in the treatment
group was 4.46 ± 0.83, and the control group was 7.34 ± 0.74 (p = 0.00). In
conclusion, there are signifcant differences in serum cortisol level decrease
and pain score between the CBT intervention with standard therapy group
compared and the standard therapy only group.
Author: Soetrisno, Sri
Sulistyowati, Supriyadi Hari Respati, Rizka Pramudhita
Journal Code: jpkedokterangg160174
