DAYA ANTIBAKTERI EKSTRAK ETANOL DAUN SENGGANI (Melastoma affine D. Don)
Abstract: Melastoma affine D.
Don had some activities such as anthelmintic, antibacteria, antiinfiammation,
antifungal, and antitumor. The aims of this research was determine antibacteria
activity of ethanolic extract of Melastoma affine D. Don. The antimicrobial activity
was tested by solid dilution method to get Minimum Inhibition Concentration
(MIC). The compounds in Melastoma affine D. Don was analyzed by tube test
method and Thin Layer Chromatography (TLC) with chloroform : methanol : formic
acid (8,5:1,5:0,5) as mobile phase and silica gel GF254 as stationary phase.
The result showed ethanolic extract of Melastoma affine D. Don contains
alkaloid, polyphenol, fiavonoid, saponin, and essential oil. The MIC of
Senggani against Staphylococcus aureus was 2% and 3% against Escherichia coli
and the extract could not inhibit Staphylococcus aureus and Escherichia coli
multiresistant until concentration 7% extract ethanol.
Penulis: Ika Trisharyanti Dian
Kusumowati, Rosita Melannisa, Angga Prasetyawan
Kode Jurnal: jpkedokterandd140563
