Correlation between Oxygen Saturation and Hemoglobin and Hematokrit Levels in Tetralogy of Fallot Patients
Abstract: Hemoglobin and
hematocrit levels increase in Tetralogy of Fallot (TOF) but the oxygen
saturation declines. Reduced hemoglobin in circulating blood as a parameter of
cyanosis does not indicate rising hemoglobin due to the ‘not-working’
hemoglobins that affect the oxygen saturation. Increasing hematocrit is the
result of secondary erythrocytosis caused by declining oxygen level in blood,
which is related to the oxygen saturation. This study was conducted to find the
correlation between oxygen saturation and hemoglobin and hematocrite levels in
TOF patients.
Methods: This study was undertaken at Dr. Hasan Sadikin General Hospital
in the period of January 2011 to December 2012 using the cross-sectional
analytic method with total sampling technique. Inclusion criteria were medical
records of TOF patients diagnosed based on echocardiography that included data
on oxygen saturation, hemoglobin, and hematocrite. Exclusion criteria was the
history of red blood transfusion.
Results: Thirty medical records of TOF patiens from Dr. Hasan Sadikin
General Hospital Bandung were included in this study. Due to skewed data
distribution, Spearman correlation test was used to analyze the data. There was
a significant negative correlation between oxygen saturation and hematocrit
level (r= -0.412; p=0.024) and insignificant correlation between oxygen
saturation and hemoglobin (r=-0.329; p= 0.076).
Conclusions: There is a weak negative correlation between oxygen
saturation and hematocrite levels.
Author: Farhatul Inayah
Adiputri, Armijn Firman, Arifin Soenggono
Journal Code: jpkedokterangg160107