Comparison of Coronary Angiography Characteristics among Acute Coronary Syndrome Patients in Young and Old Age Patients at Cipto Mangunkusumo Hospital Jakarta
ABSTRACT: to identify the
difference between coronary angiography in patients with acute coronary
syndrome (ACS) aged ≤45 years and those aged >45 years. Methods: a total of
322 ACS patients who underwent coronary angiography in ICCU of Cipto
Mangunkusumo Hospital, Jakarta between January 2008 and December 2012 were
included in this study. The severity of coronary stenosis was determined by
vessel score and coronary score. A signifcant vessel score was defned as a
stenosis of coronary vessel of >70%. Patients were divided into two groups:
those aged ≤45 years (72 cases) and those aged >45 years (250 cases). The
statistical analysis was performed with Chi-square test for categorical data
with two-unpaired groups and the t-test or Mann-Whitney for numerical data.
Results: the highest distribution of 1-VD (single-vessel disease) patients was
found the group of patients aged ≤45 years (43.1% vs 26.0%); while for 3-VD
(triple-vessel disease) patients, the highest distribution was noticed in the
group of patients aged >45 years (31.6% vs 18.1%). The stenosis score was lower
in patients aged ≤45 years compared those aged >45 years (median stenosis
score 4 vs 8), p<0.001. Atherosclerosis was found most common for the left
anterior descending artery in both age groups (65.3% and 74.0%). However, there
was less signifcant stenosis lesion for the Left Circumflex and Right Coronary
Arteries in patients aged ≤45. The result was statistically signifcant (26.4%
and 31.9% vs 46.4% and 57.2%, p=0.002 and 0.001). Conclusion: the number of
coronary artery diseases (vessel score) and stenosis score is lower in patients
aged ≤45 years compared to patients aged >45 years.
Author: Rahmad Isnanta,
Marulam M. Panggabean, Idrus Alwi
Journal Code: jpkedokterangg140277
