A cross sectional study of trihexyphenidyl utilization on patient receiving antipsychotic therapy
Abstract: Psychotic disorder
becomes a mental health problem recently that reduce quality of life of the
patient. As the matter of fact, psychotic treatment induce another problem such
as extrapyramidal symtomps (EPS). Trihexyphenidyl is the first choice as
conjuctive treatment to prevent EPS. Objective: To determine the description
and characteristics of trihexyphenidylutilization on patient with psychotic who
receive antipsychotic therapy at Ghrasia Hospital Yogyakarta.
Methods: This study is a non-experimental descriptive with cross
sectional design with the secondary data obtained from the medical record of
patients with psychotics on January 2014 – January 2015 to perceive the
utilizationof trihexyphenidyl on patient who receive antipsychotic therapy at
Ghrasia hospital. The sample is determined by Slovin formula, the data is
analyzed with univariat analysis technic.
Results: The majority of psychotic patients at the Ghrasia Hospital are
about 25-40 years old (61,7%). It describes that the pattern of the psychotic
disorder most likely happening at middle age, which 98 patients are male
(63,6%). The combination of two antipsychotics becomes the most used regiment
at Grhasia, 113 patients (73,4%) receive the combination of two antipsychotics theraphy,
39 patients (25,3%) receive single antipsychotic therapy and 2 patients (1,3%)
receive the combination of three antipsychotics. 136 patients (88,3%) receive
trihexyphenidyl twice a day on undefined skizophrenia 65 patients (42,2%) and
18 patients (11,7%) once a day. 149 patiens (96,8) are not examined before THP
is given before the initiaton of the theraphy.
Conclusion: Administration trihexiphenidyl as adjunctive therapy is given
to the psychotic patients twice a day and most of them are not initiated by the
examination of syndrome extrapyramidal.
Author: Addiniya Nurul Azmi,
Sufi Desrini
Journal Code: jpkedokterangg160163